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As mentioned in the study, administration of exenatide after SCI suppressed C/EBP homologous transcription factor protein (CHOP, a pro-apoptotic transcription factor central to ER stress-mediated apoptosis) while upregulating glucose regulatory protein 78 (GRP78, an ER chaperone with cytoprotective effects) in the injured spinal cord, leading to a significant decrease in tissue damage and a significant increase in oligodendrocyte progenitor cell survival [66]
The most common side effects in trials were gastrointestinal: nausea, diarrhea, constipation, vomiting, and decreased appetite
If you experience a headache, it is important to drink plenty of fluids and take over-the-counter pain medication if necessary
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Moderate, consistent weight loss (11.5 lbs/week) is safer than rapid drops
Encouraging safe storage practices, including following label instructions and ensuring appropriate storage conditions, supports better outcomes and reduces the risk of misuse
